Título

Predictive value of frailty indexes for adverse outcomes in older adults

Autor

MARIO ULISES PEREZ ZEPEDA

Matteo Cesari

María del Carmen García Peña

Nivel de Acceso

Acceso Abierto

Materias

MEDICINA Y CIENCIAS DE LA SALUD - (CTI) Ciencias médicas - ([Revista de Investigación Clínica (0034-8376) vol. 68 (2016)]) Ciencias clínicas - ([Revista de Investigación Clínica (0034-8376) vol. 68 (2016)]) Geriatría - ([Revista de Investigación Clínica (0034-8376) vol. 68 (2016)]) Condiciones patológicas (signos y síntomas) - ([Revista de Investigación Clínica (0034-8376) vol. 68 (2016)]) Procesos patológicos - ([Revista de Investigación Clínica (0034-8376) vol. 68 (2016)]) Fragilidad - ([Revista de Investigación Clínica (0034-8376) vol. 68 (2016)]) Salud pública - ([Revista de Investigación Clínica (0034-8376) vol. 68 (2016)]) Accidentes - ([Revista de Investigación Clínica (0034-8376) vol. 68 (2016)]) Caídas accidentales - ([Revista de Investigación Clínica (0034-8376) vol. 68 (2016)]) Personas mayores - ([Revista de Investigación Clínica (0034-8376) vol. 68 (2016)]) Geriatrics - ([Revista de Investigación Clínica (0034-8376) vol. 68 (2016)]) Pathological conditions (signs and symptoms) - ([Revista de Investigación Clínica (0034-8376) vol. 68 (2016)]) Pathologic processes - ([Revista de Investigación Clínica (0034-8376) vol. 68 (2016)]) Frailty - ([Revista de Investigación Clínica (0034-8376) vol. 68 (2016)]) Public health - ([Revista de Investigación Clínica (0034-8376) vol. 68 (2016)]) Accidents - ([Revista de Investigación Clínica (0034-8376) vol. 68 (2016)]) Accidental falls - ([Revista de Investigación Clínica (0034-8376) vol. 68 (2016)]) Aged - ([Revista de Investigación Clínica (0034-8376) vol. 68 (2016)])

Resumen o descripción

Abstract: Background: There are two widely used tools to classify frailty in older adults: the frailty phenotype and the frailty index. Both have been validated for prediction of adverse outcomes. Objective: To assess the ability of different frailty indices to predict a number of adverse outcomes (falls, disability, and mortality) by adding deficits in a fixed sequence (with the first five deficits as in the frailty phenotype: weakness, weight loss, slowness, exhaustion and low physical activity) or randomly. Methods: This is an analysis of the Costa-Rican Longevity and Healthy Aging Study in which ≥ 60-year-old adults were included and followed up for four years. Frailty indices were constructed, including the frailty phenotype components in the first five indices followed by the random addition of other deficits and estimating for each one the odds ratios for falls and disability and hazard ratios for mortality, adjusted for age and sex. Results: We included 2,708 adults; mean age was 76.31 years, 54.28% were women. Indices with the highest number of deficits had the highest estimates for each adverse outcome, independent of the deficit. Conclusion: The higher the number of deficits in an index, the higher the estimates for adverse outcomes, independent of the type of deficit added.

Editor

Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubirán

Fecha de publicación

2016

Tipo de publicación

Artículo

Formato

Adobe PDF

application/pdf

Fuente

Revista de Investigación Clínica (0034-8376) vol. 68 (2016)

Idioma

Inglés

Relación

http://clinicalandtranslationalinvestigation.com/abstract.php?id=84

Repositorio Orígen

INSTITUTO NACIONAL DE GERIATRIA

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