Título
Toxicology of antimicrobial nanoparticles for prosthetic devices
Autor
Rosa Elvira Nuñez-Anita
Laura Susana Acosta_Torres
JUAN CARLOS MARTINEZ ESPINOSA
Javier De La Fuente Hernández
VICTOR MANUEL CASTAÑO MENESES
Nivel de Acceso
Acceso Abierto
Referencia de publicación
ISSN/1178-2013
URL/https://www.dovepress.com/toxicology-of-antimicrobial-nanoparticlesfor-prosthetic-devices-peer-reviewed-article-IJN
doi: 10.2147/IJN.S63064
Materias
Cytotoxicity - (PALABRA CLAVE DEL AUTOR) Oxidative stress - (PALABRA CLAVE DEL AUTOR) Genotoxicity - (PALABRA CLAVE DEL AUTOR) Antifungal effect - (PALABRA CLAVE DEL AUTOR) Denture bases - (PALABRA CLAVE DEL AUTOR) MEDICINA Y CIENCIAS DE LA SALUD - (CTI) CIENCIAS MÉDICAS - (CTI) OTRAS ESPECIALIDADES MÉDICAS - (CTI)
Resumen o descripción
Advances in nanotechnology are producing an accelerated proliferation of new nanomaterial composites that are likely to become an important source of engineered health-related products. Nanoparticles with antifungal effects are of great interest in the formulation of microbicidal materials. Fungi are found as innocuous commensals and colonize various habitats in and on humans, especially the skin and mucosa. As growth on surfaces is a natural part of the Candida spp. lifestyle, one can expect that Candida organisms colonize prosthetic devices, such as dentures. Macromolecular systems, due to their properties, allow efficient use of these materials in various fields, including the creation of reinforced nanoparticle polymers with antimicrobial activity. This review briefly summarizes the results of studies conducted during the past decade and especially in the last few years focused on the toxicity of different antimicrobial polymers and factors influencing their activities, as well as the main applications of antimicrobial polymers in dentistry. The present study addresses aspects that are often overlooked in nanotoxicology studies, such as careful time-dependent characterization of agglomeration and ion release.
The authors thank the following DGPA-UNAM supporting programs: PAPIME-PE202214 and PAPIIT-TA200414. Victor M Castaño is on sabbatical leave at CIATEQ-Queretaro.
Editor
Dovepress
Fecha de publicación
2014
Tipo de publicación
Artículo
Versión de la publicación
Versión publicada
Recurso de información
Formato
application/pdf
Fuente
International Journal of Nanomedicine, vol. 9, no. 1, p. 3999-4006
Idioma
Inglés
Audiencia
Público en general
Repositorio Orígen
CIATEQ Digital
Descargas
832