Título

Physicochemical, mechanical, and biological properties of bone cements prepared with functionalized methacrylates

Autor

ROSSANA FARIDE VARGAS CORONADO

JUAN VALERIO CAUICH RODRIGUEZ

Nivel de Acceso

Acceso Abierto

Licencia

http://creativecommons.org/licenses/by-nc-nd/4.0

Referencia de datos

doi: DOI: 10.1177/0885328204045443

Materias

 BIOCOMPATIBILITY - (AUTORES) BONE CEMENTS - (AUTORES) DIETHYL AMINO ETHYL METHACRYLATE - (AUTORES) MECHANICAL PROPERTIES - (AUTORES) METHACRYLIC ACID - (AUTORES) OSTEOBLASTS - (AUTORES) INGENIERÍA Y TECNOLOGÍA - (CTI)

Resumen o descripción

Bone cements prepared with methyl methacrylate (MMA) as a base monomer and either methacrylic acid (MAA) or diethyl amino ethyl methacrylate (DEAEMA) as comonomers were characterized in terms of curing behavior, mechanical properties, and their in vitro biocompatibility. The curing time and setting temperature were found to be composition dependent while the residual monomer was not greatly affected by the presence of either acidic or alkaline comonomers in the bone cements. For samples with MAA comonomer, a faster curing time and higher setting temperature were observed when compared to the cement with DEAEMA comonomer. In terms of mechanical properties, the highest compressive strength was exhibited by formulations containing MAA, while the highest impact strength was shown by the formulations prepared with DEAEMA. There were no differences observed between the two formulations for tensile, shear, and bending strength values. Similarly, fatigue crack propagation studies did not reveal differences with the addition of either DEAEMA or MAA. No differences were observed in the initial number of attached primary rat femur osteoblasts on the different bone cements and positive controls. However, after 48h there was a reduced proliferation in the cells grown on bone cements containing MAA.

Fecha de publicación

2004

Tipo de publicación

Artículo

Versión de la publicación

Versión publicada

Recurso de información

http://cicy.repositorioinstitucional.mx/jspui/handle/1003/885

Formato

application/pdf

Fuente

Journal of biomaterials applications, 19(2), 147-161, 2004

Idioma

Inglés

Relación

&

Ginebra, M. P. (2004). Physicochemical, mechanical, and biological properties of bone cements prepared with functionalized methacrylates. Journal of biomaterials applications, 19(2), 147-161.

Sugerencia de citación

Sabino, M. A., Ajami, D., Salih, V., Nazhat, S. N., Vargas-Coronado, R., Cauich-Rodríguez, J. V.,

Repositorio Orígen

Repositorio Institucional CICY

Descargas

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