Título
Interaction of spermine with a signal transduction pathway involving phospholipase C, during the growth of Catharanthus roseus transformed roots
Autor
ILEANA DE LA CARIDAD ECHEVARRIA MACHADO
ANGELA FRANCISCA KU GONZALEZ
VICTOR MANUEL LOYOLA VARGAS
SOLEDAD MARIA TERESA HERNANDEZ SOTOMAYOR
Nivel de Acceso
Acceso Abierto
Referencia de datos
doi: https://doi.org/10.1111/j.0031-9317.2004.0212.x
Materias
Resumen o descripción
In Cantharanthus roseus transformed roots, the application of methylglyoxal bis(guanylhydrazone) (MGBG), an inhibitor of S-adenosylmethionine decarboxylase (SAMDC; EC 4.1.1.50), inhibited the root growth in a dose-dependent manner with a DL50 of about 300 μm. Spermidine and spermine (Spm) levels and SAMDC and phospholipase C (PLC; EC 3.1.4.3) activities were reduced in the presence of the inhibitor. The inhibition was reversed by the addition of Spm. Radioactivity from [14C[Spm was detected in an immunoprecipitated fraction with an antibody anti-PLC-δ. To our knowledge, this is the first direct evidence that demonstrates an interaction of Spm with the signal transduction cascade phosphoinositide-Ca 2+.
Fecha de publicación
2004
Tipo de publicación
Artículo
Versión de la publicación
Versión publicada
Recurso de información
Formato
application/pdf
Fuente
Physiologia plantarum, 120(1), 140-151, 2004
Idioma
Español
Relación
&
Hernández‐Sotomayor, S. M. (2004). Interaction of spermine with a signal transduction pathway involving phospholipase C, during the growth of Catharanthus roseus transformed roots. Physiologia plantarum, 120(1), 140-151.
Sugerencia de citación
Echevarría‐Machado, I., Ku‐González, A., Loyola‐Vargas, V. M.,
Repositorio Orígen
Repositorio Institucional CICY
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