Título

Interaction of spermine with a signal transduction pathway involving phospholipase C, during the growth of Catharanthus roseus transformed roots

Autor

ILEANA DE LA CARIDAD ECHEVARRIA MACHADO

ANGELA FRANCISCA KU GONZALEZ

VICTOR MANUEL LOYOLA VARGAS

SOLEDAD MARIA TERESA HERNANDEZ SOTOMAYOR

Nivel de Acceso

Acceso Abierto

Referencia de datos

doi: https://doi.org/10.1111/j.0031-9317.2004.0212.x

Resumen o descripción

In Cantharanthus roseus transformed roots, the application of methylglyoxal bis(guanylhydrazone) (MGBG), an inhibitor of S-adenosylmethionine decarboxylase (SAMDC; EC 4.1.1.50), inhibited the root growth in a dose-dependent manner with a DL50 of about 300 μm. Spermidine and spermine (Spm) levels and SAMDC and phospholipase C (PLC; EC 3.1.4.3) activities were reduced in the presence of the inhibitor. The inhibition was reversed by the addition of Spm. Radioactivity from [14C[Spm was detected in an immunoprecipitated fraction with an antibody anti-PLC-δ. To our knowledge, this is the first direct evidence that demonstrates an interaction of Spm with the signal transduction cascade phosphoinositide-Ca 2+.

Fecha de publicación

2004

Tipo de publicación

Artículo

Versión de la publicación

Versión publicada

Formato

application/pdf

Fuente

Physiologia plantarum, 120(1), 140-151, 2004

Idioma

Español

Relación

&

Hernández‐Sotomayor, S. M. (2004). Interaction of spermine with a signal transduction pathway involving phospholipase C, during the growth of Catharanthus roseus transformed roots. Physiologia plantarum, 120(1), 140-151.

Sugerencia de citación

Echevarría‐Machado, I., Ku‐González, A., Loyola‐Vargas, V. M.,

Repositorio Orígen

Repositorio Institucional CICY

Descargas

271

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