Título

Occurrence of killer Candida glabrata clinical isolates

Autor

OMAR ELIND ARROYO HELGUERA

ALEJANDRO DE LAS PEÑAS NAVA

IRENE BEATRIZ CASTAÑO NAVARRO

Nivel de Acceso

Acceso Abierto

Identificador alterno

doi: http://dx.doi.org/10.1590/S1517-83822012000300005

Resumen o descripción

"In this work we characterized the occurrence of killer activity in 64 Candida glabrata clinical isolates under different conditions. We found that only 6.25 % of the clinical isolates tested were positive for killer activity against a Saccharomyces cerevisiae W303 sensitive strain. Sensitivity of killer activity to different values of pH and temperatures was analyzed. We found that the killer activity presented by all isolates was resistant to every pH and temperature tested, although optimal activity was found at a range of pH values from 4 to 7 and at 37ºC. We did not observe extrachromosomal genetic elements associated with killer activity in any of the positive C. glabrata isolates. The killer effect was due to a decrease in viability and DNA fragmentation in sensitive yeast."

Editor

Sociedade Brasileira de Microbiologia

Fecha de publicación

2012

Tipo de publicación

Artículo

Versión de la publicación

Versión publicada

Formato

application/pdf

Idioma

Inglés

Relación

&

Irene, Castaño. (2012). Occurrence of killer Candida glabrata clinical isolates. Brazilian Journal of Microbiology, 43(3), 880-887. https://dx.doi.org/10.1590/S1517-83822012000300005

Audiencia

Público en general

Sugerencia de citación

O, Arroyo-Helguera, Alejandro, De Las Penas,

Repositorio Orígen

Repositorio IPICYT

Descargas

328

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