Título

Expansion of human hematopoietic stem cells for transplantation: trends and perspectives

Autor

Hera Andrade Zaldívar

MARTHA LETICIA SANTOS MARTINEZ

Antonio de León Rodríguez

Nivel de Acceso

Acceso Abierto

Licencia

http://creativecommons.org/licenses/by-nc-nd/4.0

Identificador alterno

doi: https://doi.org/10.1007/s10616-008-9144-1

Materias

2D-culture - (AUTOR) 3D-culture - (AUTOR) Human cells - (AUTOR) Leukemia - (AUTOR) Rotating wall vessel - (AUTOR) Stirred tank - (AUTOR) Transplant - (AUTOR) CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA - (CTI) CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA - (CTI)

Resumen o descripción

"Umbilical cord blood transplantation is clinically limited by its low progenitor cell content. Ex vivo expansion has become an alternative to increase the cell dose available for transplants. Expansion has been evaluated in several ways such as static cultures combining growth factors or mimicking the natural microenvironment using co-culture systems. However, static cultures have a small volume capacity and therefore large-scale expansion has been addressed using bioreactors. These and other biotechnological approaches for the expansion of hematopoietic progenitors and their utility to study several aspects of hematopoietic stem cell biology are discussed here."

Editor

Springer

Fecha de publicación

marzo de 2008

Tipo de publicación

Artículo

Versión de la publicación

Versión aceptada

Recurso de información

http://ipicyt.repositorioinstitucional.mx/jspui/handle/1010/1473

Formato

application/pdf

Relación

&

De León Rodríguez, A. Cytotechnology (2008) 56: 151. https://doi.org/10.1007/s10616-008-9144-1

Sugerencia de citación

Andrade-Zaldívar, H., Santos, L.

Repositorio Orígen

Repositorio IPICYT

Descargas

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