Título
Physiology and Pathology of Innate Immune Response Against Pathogens
Autor
MARIA ALEJANDRA MORENO GARCIA
Nivel de Acceso
Acceso Abierto
Materias
Resumen o descripción
Pathogen infections are recognized by the immune system, which consists of two types
of responses: an innate immune response and an antigen-specific adaptive immune
response. The innate response is characterized by being the first line of defense that occurs
rapidly in which leukocytes such as neutrophils, monocytes, macrophages, eosinophils,
mast cells, dendritic cells, etc., are involved. These cells recognize the pathogen-associated
molecular patterns (PAMPs), which have been evolutionarily conserved by the diversity
of microorganisms that infect humans. Recognition of these pathogen-associated molecular
patterns occurs through pattern recognition receptors such as Toll-like receptors and
some other intracellular receptors such as nucleotide oligomerization domain (NOD),
with the aim of amplifying the inflammation and activating the adaptive cellular immune
response, through the antigenic presentation. In the present chapter, we will review the
importance of the main components involved in the innate immune response, such as different
cell types, inflammatory response, soluble immune mediators and effector mechanisms
exerted by the immune response against bacteria, viruses, fungi, and parasites; all
with the purpose of eliminating them and eradicating the infection of the host.
Producción Científica de la Universidad Autónoma de Zacatecas UAZ
Fecha de publicación
20 de diciembre de 2017
Tipo de publicación
Capítulo de libro
Recurso de información
http://localhost/xmlui/handle/20.500.11845/680
978-953-51-3692-7
Formato
application/pdf
Idioma
Inglés
Audiencia
Público en general
Repositorio Orígen
Repositorio Institucional Caxcán
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