Título
Self-report prevalence and associated factors to drug hypersensitivity in Mexican young adults
Autor
MARTIN BEDOLLA BARAJAS
CECILIA PUENTE FERNANDEZ
MIRIAM VERONICA FLORES MERINO
JAIME MORALES ROMERO
MA VICTORIA DOMINGUEZ GARCIA
Nivel de Acceso
Acceso Abierto
Materias
Drug hypersensitivity - ([2233-8268, 2233-8276]) - ([2233-8268, 2233-8276]) Prevalence - ([2233-8268, 2233-8276]) - ([2233-8268, 2233-8276]) Risk factors - ([2233-8268, 2233-8276]) - ([2233-8268, 2233-8276]) Young adult - ([2233-8268, 2233-8276]) - ([2233-8268, 2233-8276]) MEDICINA Y CIENCIAS DE LA SALUD - (CTI)
Resumen o descripción
Background: Drug hypersensitivity is defined as any unfavorable reaction that occurs after the administration of any drug. It may
or may not be mediated by the involvement of the immune system. Epidemiological data related to drug hypersensitivity reactions
in our country are scarce.
Objective: To determine the prevalence of drug hypersensitivity in a group of young adults, as well as to identify associated
factors.
Methods: A structured questionnaire was applied to young people aged 18 to 25 years. The instrument was oriented to identify
reactions of drug hypersensitivity, as well as the most prevalent drugs involved. In addition, a personal and family history of atopic
diseases was included. Analysis for associations between variables was been done through logistic regression.
Results: The prevalence of drug hypersensitivity reactions was 12% (144 of 1,200). The antibiotics were the agents most related
to hypersensitivity reactions (9.8%) followed by nonsteroidal anti-inflammatory drugs (1.6%). Factors associated with drug
hypersensitivity were a personal history of asthma, odds ratio (OR) 3.15 (95% confidence interval [CI], 1.44–6.91), maternal and
paternal history of drug hypersensitivity, OR 2.33 (95% CI, 1.21–4.48) and OR 3.11 (95% CI, 1.22–7.92), respectively.
Conclusion: The results of this research show that drug hypersensitivity in young adults is a highly prevalent event and it is
associated with personal history of asthma and history of drug hypersensitivity in parents.
Editor
Asia Pacific Association of Allergy, Asthma and Clinical Immunology
Fecha de publicación
19 de julio de 2017
Tipo de publicación
Artículo
Recurso de información
Fuente
2233-8268
2233-8276
Idioma
Inglés
Audiencia
Estudiantes
Investigadores
Repositorio Orígen
REPOSITORIO INSTITUCIONAL DE LA UAEM
Descargas
206