Título
Atypical Klebsiella Species in a Third Level Hospital as Cause of Neonatal Infection
Autor
DAMIAN DAVID CIFUENTES CASTANEDA
NINFA RAMIREZ DURAN
ILIANA ESPINOZA RIVERA
LUZ MARCELA CARO GONZALEZ
Martín Antonio Pablo Moreno Pérez
HUGO MENDIETA ZERON
Nivel de Acceso
Acceso Abierto
Materias
Resumen o descripción
Aportamos una propuesta para analizar la agresividad de un patógeno en relación a la resistencia y sensibilidad antimicrobianas encontradas.
Background: The opportunistic pathogen Klebsiella pneumoniae is one of the main causes of pediatric bacterial blood stream infections (BSI), which is complicated with sepsis and high mortality. Objectives: To identify atypical Klebsiella species affecting a sample of infected neonates with low antimicrobial response. Methods: Multidrug resistant blood cultures for Klebsiella from a Neonatal Service, were submitted to molecular identification by sequencing analysis of 16S ribosomal RNA. Results: Themean age of the newborns was 14.7±5.6 days. A total of 6 out of 8 cases were sepsis, 1 case of pneumonia, and 1 a catheterrelated infection. The molecular identification showed 3 cases of K. pneumoniae subsp. ozaenae, 2 of K. pneumoniae and K. variicola, and 1 case of K. oxytoca. The highest antimicrobial resistance was against cephalosporins and Trimethoprim/sulfamethoxazole. Conclusions: Klebsiella pneumoniae subsp. ozaenae was responsible for multidrug resistant strains of Klebsiella even in 37.5% of cases. In our clinical setting, the use of Amikacin and carbapenems are still useful to treat neonatal infections by Klebsiella even against K. variicola, which is the most resistant
Ciprés Grupo Médico S.C. (CGM).
Editor
Jundishapur J Microbiol.
Fecha de publicación
13 de febrero de 2018
Tipo de publicación
Artículo
Recurso de información
Fuente
2008-4161
Idioma
Inglés
Audiencia
Estudiantes
Investigadores
Repositorio Orígen
REPOSITORIO INSTITUCIONAL DE LA UAEM
Descargas
449