Título
High relative abundance of firmicutes and increased TNF- ¿ levels correlate with obesity in children.
Autor
YANETH CITLALLI ORBE ORIHUELA
ALFREDO LAGUNAS MARTINEZ
MARGARITA BAHENA ROMAN
Vicente Madrid Marina
KIRVIS JANNETH TORRES POVEDA
EUGENIA FLORES ALFARO
CINTHYA ESTEFHANY DIAZ BENITEZ
OSCAR PERALTA ZARAGOZA
ANA ISABEL BURGUETE GARCIA
Nivel de Acceso
Acceso Abierto
Materias
Resumen o descripción
To investigate the correlation among pro- or anti-inflammatory cytokines and the two main gut microbiota phyla in obese children. Materials and methods. Anthropometric data were obtained from 890 children under 14 years old to determine the degree of obesity. Serum cytokine concentration was measured by ELISA. Relative abundance of gut microbiota in feces was evaluated by quantitative Real-Time PCR assays. Results. Anthropometric and biochemical parameters were statistically higher in overweight /obese children than in lean ones. Increased TNF-¿ levels were found in obese children that also have a high relative abundance of Firmicutes. Conclusions. Obese children have a high relative abundance of Firmicutes that correlates with increased levels of TNF-¿. This is the first study that shows a relation between Firmicute abundance and TNF-¿ serum concentration in obese children.
Editor
Salud Pública de México
Fecha de publicación
24 de febrero de 2017
Tipo de publicación
Artículo
Recurso de información
Formato
application/pdf
Idioma
Español
Audiencia
Público en general
Repositorio Orígen
Repositorio Institucional de Ciencia Abierta de la Universidad Autónoma de Guerrero
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