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Selecciona los temas de tu interés y recibe en tu correo las publicaciones más actuales
Saúl Alejandro Rodríguez Jiménez LEONOR ADRIANA CARDENAS ROBLEDO (2023, [Artículo])
This paper develops a device capable of confirming the minimum coverage area on a thermistor by a thermal paste dispensed and cured in the manufacturing process of Exhaust Gas Recirculation (EGR) temperature sensors to provide the required fixation in the presence of mechanical shock conditions. Such a device leverages the thermistor’s self-heating effect and the thermal conductivity of the paste to read the voltage drop from the sensor, which translates into paste coverage area. The methodology follows a synthesized procedure to develop equipment and processes, considering an early phase for concept confirmation to demonstrate the feasibility of the device development. In a later phase, the optimal parameters are calculated and set to the device for delivering the corresponding classification of the sensors during the test. Once launched in production, the device demonstrates high effectiveness in screening out the sensors with rejectable paste coverage area on the thermistor.
Self-heating effect Thermistor Paste Temperature sensor Heat dissipation INGENIERÍA Y TECNOLOGÍA CIENCIAS TECNOLÓGICAS OTRAS ESPECIALIDADES TECNOLÓGICAS OTRAS OTRAS
Alison Bentley Charles Chen Nunzio D'Agostino (2022, [Artículo])
Allele Mining High-Throughput Phenotyping Genomic Estimated Breeding Value CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA CROP IMPROVEMENT DNA CHROMOSOME MAPPING GENETIC LINKAGE GENOMES GENOTYPING GERMINATION HEAT STRESS QUALITY CONTROL SINGLE NUCLEOTIDE POLYMORPHISM TRITICUM AESTIVUM GENETIC DIVERSITY (AS RESOURCE) HIGH-THROUGHPUT SEQUENCING
Atul Kulkarni Keshab Babu Koirala Pervez Zaidi (2023, [Artículo])
Inverse Probability Weighted Regression Heat Tolerant Maize Hybrid Partial Budget CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA HEAT STRESS HEAT TOLERANCE MAIZE HYBRIDS BUDGETS YIELDS
Willingness to pay (WTP) for heat-tolerant maize hybrids in the Mid-Western Terai region of Nepal
Atul Kulkarni Keshab Babu Koirala Pervez Zaidi (2023, [Artículo])
Heat-Tolerant Maize Hybrid Preference Heterogeneity CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA HEAT TOLERANCE MAIZE HYBRIDS WILLINGNESS TO PAY CONTINGENT VALUATION
Evaluación de un derivado de la Adenosina sobre la metástasis ósea inducida por el cáncer de mama
Citlalli Oyuki Mendoza Chacón (2024, [Tesis de maestría])
El cáncer de mama (CM) es considerado como el tipo de cáncer con mayor incidencia y la principal causa de muerte en mujeres en el mundo. Cuando el cáncer está avanzado y ha migrado a otros órganos y específicamente a los huesos, se conoce como metástasis ósea. Los tratamientos actuales ofrecen a los pacientes un panorama favorable cuando el cáncer está en estadio temprano; sin embargo, aún no existe una terapia que cure la metástasis ósea. La adenosina y sus derivados han demostrado su potencial en la regulación del crecimiento tumoral y la supervivencia de las células cancerosas. Por lo tanto, este trabajo tuvo como objetivo evaluar el potencial anticancerígeno de un derivado de la adenosina (IFC 305) sobre células de cáncer de mama 4T1 in vitro mediante ensayos de proliferación, migración, ciclo celular y apoptosis; así mismo, su efecto en un modelo in vivo de metástasis ósea. Los datos demuestran que el fármaco IFC 305 disminuye la proliferación y migración de la línea celular 4T1 dependiendo de la concentración utilizada. Por otro lado, no induce apoptosis a las 24 horas de tratamiento, pero sí un arresto del ciclo celular en la fase G0/G1. Sin embargo, el tratamiento con IFC 305 de ratones con metástasis ósea, no tuvo efecto en la disminución de las lesiones osteolíticas. Estudios futuros son necesarios para optimizar la dosis y tratamiento necesario para el modelo in vivo. En conclusión, nuestro trabajo demostró el potencial anticancerígeno del IFC 305 en ensayos in vitro, a través de la inhibición del crecimiento celular y la migración de las células cancerígenas, y sienta las bases para futuros estudios in vivo que demuestren su potencial terapéutico para el tratamiento de la metástasis ósea causada por el cáncer de mama.
Breast cancer is the type of cancer with the highest incidence and the leading cause of death in women due to this condition. When cancer cells migrate to other organs, especially bones, it is known as bone metastasis. Although the prognosis for some patients may be favorable due to early detection and treatment, there is still no therapy to cure bone metastasis by breast cancer. Adenosine and its derivatives have demonstrated their relevance in controlling proliferation, immune response, and apoptosis in different types of cancer. In this project, the anticancer potential of the drug IFC 305, a derivative of adenosine, on bone metastasis induced by breast cancer was evaluated both in vitro and in vivo. To evaluate the effect of IFC 305 on cell proliferation and migration of the 4T1 murine breast cancer cell line, the MTT assay and wound healing assay were used, respectively. The drug inhibited the proliferation and migration of 4T1 cells in a dose-dependent manner. To understand the underlying mechanism, apoptosis and the cell cycle were analyzed by flow cytometry. Results showed that after 24 hours of exposure to the drug, the effect on apoptosis is minimal. However, it was found that 4T1 cells were arrested in the G0/G1 phase of the cell cycle. However, IFC 305 treatment of mice with bone metastasis did not reduce osteolytic lesions. Future studies are necessary to optimize the dose and treatment necessary for the in vivo model. In conclusion, our work demonstrates the anticancer potential of IFC 305 on in vitro assays, through the inhibition of cell growth and migration of cancer cells. These studies seed the bases for future in vivo studies that demonstrate the IFC 305 therapeutic potential for the treatment of bone metastasis caused by breast cancer.
cáncer de mama, tratamientos, derivado de adenosina, metástasis Breast cancer, treatments, adenosine derivate, metastasis BIOLOGÍA Y QUÍMICA CIENCIAS DE LA VIDA BIOLOGÍA CELULAR OTRAS OTRAS
Sandesh Thapa Darbin Joshi (2022, [Artículo])
Heat Resilient Maize Phenotypic Coefficient of Variation Heritable Traits CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA GENETIC PARAMETERS MAIZE HYBRIDS
Low thermal conductivity solar domestic water heater
MIGUEL ANGEL PORTA GANDARA JOSE LUIS FERNANDEZ ZAYAS JUAN FRANCISCO VILLA MEDINA NORBERTO CHARGOY DEL VALLE (2022, [Artículo])
"Solar domestic water heaters (SWH) with thermosyphon circulation are the most common commercial applications of solar energy in Mexico. They are also becoming popular in the rest of the world, given their simplicity, good economic returns, and sustainability. Traditionally the solar collector, the piping, and the storage tank are built of copper and steel. However, wáter quality in many parts of the Mexican Northwest has high mineral contents and, when heated, results in early metal pitting corrosion of SWH parts. Short-lived water heaters are bad promoters of the technology. In this work, a SWH thermoplastic Chlorinated Polyvinyl Chloride (CPVC) is built and tested under real operating conditions in La Paz, BCS, Mexico. The optimal design is detected with the aid of a suitable numerical model. Results reveal that a full SWH-CPVC can be technically and economically convenient for the weather conditions of the Northwestern states of Mexico."
Low thermal conductivity solar water heater CPVC solar water heater Solar water heater cooper pitting corrosion Thermosiphon circulation INGENIERÍA Y TECNOLOGÍA CIENCIAS TECNOLÓGICAS TECNOLOGÍA ELECTRÓNICA DISPOSITIVOS TERMOELÉCTRICOS DISPOSITIVOS TERMOELÉCTRICOS
VICTOR MANUEL ZEZATTI FLORES GUSTAVO URQUIZA BELTRAN MIGUEL ANGEL BASURTO PENSADO LAURA LILIA CASTRO GOMEZ JUAN CARLOS GARCIA CASTREJON (2022, [Artículo])
This research is based on the operation tube heat exchangers, their use and problematic on hydroelectric power plants. It is based on the design heat exchanger tubes for industrial use, which took the parameters of operation, design, working fluids (air and water) and conditions to assemble a monitoring equipment at appropriate scale for the laboratory, with the necessary measurement instruments to analyze the behavior of heat energy transfer by means of thermocouples, the velocity of the air with a hot wire anemometer and the flow of water with a turbine flow meter, in pipes of different materials: copper, steel 1018 and stainless steel 316L, all in ideal conditions, and with this to found a comparative parameter with pipes of the same materials but under conditions of deterioration with the presence of forced oxidation and with the data mining and support vector machine can be minimized the corrosion problems in pipes.
INGENIERÍA Y TECNOLOGÍA CIENCIAS TECNOLÓGICAS Data mining, Support Vector Machine, Pattern Recognition and Decision Support System, Heat exchangers
VICTOR MANUEL ZEZATTI FLORES GUSTAVO URQUIZA BELTRAN MIGUEL ANGEL BASURTO PENSADO LAURA LILIA CASTRO GOMEZ (2019, [Artículo])
This research is based on the operation tube heat exchangers, their use and problematic on hydroelectric power plants. It is based on the design heat exchanger tubes for industrial use, which took the parameters of operation, design, working fluids (air and water) and conditions to assemble a monitoring equipment at appropriate scale for the laboratory, with the necessary measurement instruments to analyze the behavior of heat energy transfer by means of thermocouples, the velocity of the air with a hot wire anemometer and the flow of water with a turbine flow meter, in pipes of different materials: copper, steel 1018 and stainless steel 316L, all in ideal conditions, and with this to found a comparative parameter with pipes of the same materials but under conditions of deterioration with the presence of forced oxidation and with the data mining and support vector machine can be minimized the corrosion problems in pipes.
INGENIERÍA Y TECNOLOGÍA CIENCIAS TECNOLÓGICAS Data Mining, Support Vector Machine, Pattern Recognition and Decision Support System, heat exchangers.