Synthetic libraries of shark vNAR domains with different cysteine numbers within the CDR3

OLIVIA CABANILLAS BERNAL (2019, [Artículo])

The variable domain of New Antigen Receptors (vNAR) from sharks, present special characteristics in comparison to the conventional antibody molecules such as: small size (12–15 kDa), thermal and chemical stability and great tissue penetration, that makes them a good alternative source as therapeutic or diagnostic agents. Therefore, it is essential to improve techniques used for the development and selection of vNAR antibodies that recognize distinct antigens. The development of synthetic antibody libraries offers a fast option for the generation of antibodies with the desired characteristics. In this work three synthetic antibody libraries were constructed; without cysteines (Cys), with one Cys and with two Cys residues within its CDR3, with the objective of determining whether the presence or absence of Cys in the CDR3 favors the isolation of vNAR clones from a synthetic library. The libraries were validated selecting against six mammalian proteins. At least one vNAR was found for each of the antigens, and a clone coming from the library without Cys in the CDR3 was selected with all the antigens. In vitro angiogenesis assay with the isolated anti-VEGF antibodies, suggest that these vNARs are capable of inhibiting in vitro angiogenesis. In silico analysis of anti-VEGF antibodies showed that vNARs from synthetic libraries could rival antibodies with affinity maturation by in silico modeling. © 2019 Cabanillas-Bernal et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

aquaporin 1, carcinoembryonic antigen, cysteine, fibroblast growth factor 2, glycophorin A, leukemia inhibitory factor, vasculotropin, vasculotropin antibody, angiogenesis inhibitor, antibody, cysteine, lymphocyte antigen receptor, vasculotropin A, a BIOLOGÍA Y QUÍMICA CIENCIAS DE LA VIDA BIOFÍSICA BIOFÍSICA

Ecología Forense: al rescate de los manglares

Diana Jacqueline Cisneros de la Cruz JORGE ALFREDO HERRERA SILVEIRA CLAUDIA TEUTLI HERNANDEZ (2022, [Artículo])

Cuando hablamos de series en la tv, no cabe duda de que las más populares son las de detectives y forenses que resuelven crímenes. Pero ¿ecología forense en manglares? Si, cuando los manglares mueren o se degradan, antes de cualquier intento de rescate, o mejor dicho, de restauración, es fundamental descubrir cuál fue la causa. La ecología forense durante la restauración ecológica de manglares es parte de una estrategia que, además de la cooperación entre diferentes sectores, será fundamental para recuperar diversos servicios que nos brindan los manglares y con ello ser aliados ante el cambio climático.

CAMBIO CLIMATICO CARBONO AZUL ECOSISTEMAS COSTEROS RESTAURACION ECOLOGICA VARIABLES INDICADORAS BIOLOGÍA Y QUÍMICA CIENCIAS DE LA VIDA BIOLOGÍA VEGETAL (BOTÁNICA) ECOLOGÍA VEGETAL ECOLOGÍA VEGETAL

Economic valuation of climate induced losses to aquaculture for evaluating climate information services in Bangladesh

Peerzadi Rumana Hossain T.S Amjath-Babu Timothy Joseph Krupnik (2023, [Artículo])

Very little research has focused on climate impacts on aquaculture and the potential of climate information services (CIS) for aquaculture to support sustainable development goals 2030 (SDGs)1. This study represents an effort to bridge this gap by conducting a first ex-ante economic evaluation of CIS for aquaculture in Bangladesh by semi-automating the extraction of data on climate-induced fish losses during 2011 to 2021 from popular online newspaper articles and corroborating them with available government and satellite datasets. During this period, Bangladesh faced an estimated loss of around 140 million USD for hatcheries, open water fish and shrimp. When validated with a year of country-wide official data on climate-induced economic losses to aquaculture, the damage reported from these media sources is approximately 10 percent of actual losses. Given this rule of thumb, the potential economic value of aquacultural CIS could be up to USD14 million a year, if 10 percent of the damage can be offset by appropriate services through a range of multi-sector efforts to establish and extend these services to farmers at scale.

Climate Information Services Newspaper Scraping CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA LOSSES AQUACULTURE CLIMATE SERVICES SUSTAINABLE DEVELOPMENT GOALS

Implementation new tools and technologies in the GMP Africa Breeding Pipelines

Yoseph Beyene (2023, [Objeto de congreso])

CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA NEW TECHNOLOGY BREEDING PIPES GERMPLASM PHENOTYPING

Revisiting the phylogeny and taxonomy of the Pithecellobium clade (Leguminosae, Caesalpinioideae) with new generic circumscriptions

Iván Tamayo-Cen Benjamin Torke JOSE ENRIQUE LOPEZ CONTRERAS GERMAN CARNEVALI FERNANDEZ CONCHA Ivón Mercedes Ramírez Morillo Lilia Lorena Can Itza RODRIGO STEFANO DUNO (2022, [Artículo])

We present the most complete molecular phylogeny to date of the Pithecellobium clade of subfamily Caesalpinioideae. This neotropical group was informally recognised (as the Pithecellobium alliance) at the end of the 20th century by Barneby and Grimes (1996) and includes five genera and 33 species distributed from the southern United States and Caribbean Islands to north-eastern South America. Our aims were to further test the monophyly of the group and its genera and to identify sister group relationships within and amongst the genera. A phylogenetic analysis of nuclear ribosomal DNA sequences (ITS and ETS) was performed. The results provide further support for the monophyly of the Pithecellobium clade. The genera Ebenopsis, Pithecellobium and Sphinga were strongly supported as monophyletic. Havardia and Painteria were found to be non-monophyletic, prompting their re-circumscriptions and the description of two new genera: Gretheria and Ricoa. New combinations are made for the three species transferred to the new genera. © Iván Tamayo-Cen et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

FABACEAE INGEAE INGOID CLADE MIMOSOID NEW WORLD PHYLOGENETIC SYSTEMATIC TAXONOMY BIOLOGÍA Y QUÍMICA CIENCIAS DE LA VIDA BIOLOGÍA VEGETAL (BOTÁNICA) TAXONOMÍA VEGETAL TAXONOMÍA VEGETAL

Intimate partner violence and its relationship to labor income

Yei Javier Zepeda Hernández Alma Sofia Santillan (2024, [Artículo, Artículo])

In Mexico, 70.1% of women have been victims of violence in their lifetime and the main perpetrator is her intimate partner. Gender violence is a public health problem that has multiple negative impacts in woman and their offsprings. The relation violence and income is an issue that has been scarcely studied for Mexico. The objective of this article is to analyze the intimate partner violence and its relationship to labor income for Mexican women, data used are from the National Survey on the Dynamics of Households Relationships (ENDIREH 2021). The principal component method is used to estimate five kinds of violence; physical, emotional, economic, sexual and, harassment. The instrumental variables method is used to consider the endogeneity of income and violence variables. Except harassment, the results indicate a negative relationship between income and violence. Specifically, sexual violence has the greatest negative effects; women who are victims of sexual violence have an average reduction of 17.4% in monthly labor income. This negative effect represents a loss of just over two month of working days per year and, in the aggregate terms, is equivalent to 0.87% of GDP. The above highlights the importance of orienting public policy actions to work in prevention, attention, punishment and eradications any kind of violence against women. 

Intimate partner violence Labor income Endogeneity Instrumental variables Cost of violence Violencia de pareja Ingresos laborales Endogeneidad Variables instrumentales Costo de la violencia. CIENCIAS SOCIALES CIENCIAS SOCIALES

Predicción de la evapotranspiración de referencia mediante redes neuronales artificiales

JUAN MANUEL GONZALEZ CAMACHO ROCIO CERVANTES-OSORNIO WALDO OJEDA BUSTAMANTE IRINEO LORENZO LOPEZ CRUZ (2008, [Artículo])

La evapotranspiración de referencia (ETo) es una variable climática esencial para el cálculo de los requerimientos hídricos de los cultivos. Su previsión a corto plazo es importante para programar la distribución de volúmenes de agua en las zonas de riego. En este trabajo se presenta la aplicación de un modelo de Red Neuronal Artificial (RNA) tipo feedforward backpropagation para predecir la ETo a partir de datos diarios de temperatura del aire, radiación solar, humedad relativa y velocidad del viento. La arquitectura adoptada del modelo de RNA contiene cuatro neuronas en la capa intermedia, una neurona en la capa de salida y funciones de activación tangente hiperbólica en ambas capas. Este modelo fue aplicado a un conjunto de datos climáticos con cinco años de observaciones de la red agroclimática “Valle del Fuerte” del distrito de riego 075, localizada en el norte de Sinaloa, México. El algoritmo de entrenamiento supervisado de Levenberg-Marquardt permitió obtener un buen desempeño de la red en términos del error cuadrático medio y del coeficiente de determinación R2 para estimar la ETo en los diferentes escenarios considerados. Las predicciones de las RNA fueron comparadas con las predicciones de modelos de regresión lineal múltiple y lineal por partes; los resultados muestran que ambos modelos presentan niveles de ajuste muy similares a los datos experimentales.

Evapotranspiración Requerimientos de riego Variables climáticas Distritos de riego Regresión no lineal Redes neuronales artificiales CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA

Worldwide selection footprints for drought and heat in bread wheat (Triticum aestivum L.)

Ana Luisa Gómez Espejo Carolina Sansaloni Juan Burgueño Fernando Henrique Toledo Adalberto Benavides-Mendoza M. Humberto Reyes-Valdés (2022, [Artículo])

Genome–Environment Associations Climatic Variables Hormonal Elicitors CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA ADAPTATION DROUGHT STRESS HEAT STRESS LANDRACES TRITICUM AESTIVUM

2022 Advanced wheat improvement course: Global wheat rust surveillance

&

monitoring

David Hodson (2022, [Objeto de congreso])

CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA WHEAT RUSTS DISEASE SURVEILLANCE NEW TECHNOLOGY REMOTE SENSING

Global rust monitoring

David Hodson (2022, [Objeto de congreso])

CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA WHEAT RUSTS DISEASE SURVEILLANCE REMOTE SENSING NEW TECHNOLOGY