GENERACIÓN DE HACES ESTRUCTURADOS PARCIALMENTE COHERENTES

Maria Fernanda Arvizu Soto (2024, [Tesis de maestría])

"Mediante la manipulación de la intensidad, polarización y fase de un campo luminoso es como podemos obtener luz estructurada. Los estudios han demostrado que los haces parcialmente coherentes son más resistentes a las fluctuaciones atmosféricas. En esta tesis presentamos el modelo matemático, la generación computacional del Haz Vectorial Parcialmente Coherente (PCVB) y dos configuraciones experimentales para generarlos con la ayuda de un Dispositivo Micro Espejo Digital (DMD). Los resultados teóricos esperados concuerdan con las simulaciones y allanan el camino para otros resultados teóricos y experimentales, que se dejan como trabajo futuro."

Luz estructurada Haces vectoriales Coherencia parcial Dispositivo digital de microespejos CIENCIAS FÍSICO MATEMÁTICAS Y CIENCIAS DE LA TIERRA FÍSICA ÓPTICA OPTICA FÍSICA OPTICA FÍSICA

GENERATION OF LG VECTOR MODES WITH ULTRAHIGH STABILITY BASED ON COMPLEX AMPLITUDE MODULATION IN AN ON-AXIS CONFIGURATION

Gloria Elizabth Rodríguez García (2023, [Tesis de maestría])

"This thesis presents a novel technique for generating vector beams using complex amplitude modulation (CAM) in an on-axis configuration. The holograms used to generate the beams were created using the Mathlab software and displayed on a reflective spatial light modulator (SLM). The main goal of this research was to address both the purity and stability of the beams during generation and propagation, introducing a quantitative approach to assess their stability. As a proof-of-concept, Laguerre-Gaussian vector beams have been generated and characterized using Stokes polarimetry with the proposed experimental set up."

Structured light Laguerre-Gauss vector beams Stokes polarimetry Beam generation Spatial light modulators CIENCIAS FÍSICO MATEMÁTICAS Y CIENCIAS DE LA TIERRA FÍSICA ÓPTICA OPTICA FÍSICA OPTICA FÍSICA

OPTIMIZING THE TRANSFER OF ENERGY IN A HEAT EXCHANGER MINIMIZING THE CORROSION PROBLEMS IN PIPES IN A HYDROELECTRIC POWER STATION USING DATA MINING AND SUPPORT VECTOR MACHINE

VICTOR MANUEL ZEZATTI FLORES GUSTAVO URQUIZA BELTRAN MIGUEL ANGEL BASURTO PENSADO LAURA LILIA CASTRO GOMEZ (2019, [Artículo])

This research is based on the operation tube heat exchangers, their use and problematic on hydroelectric power plants. It is based on the design heat exchanger tubes for industrial use, which took the parameters of operation, design, working fluids (air and water) and conditions to assemble a monitoring equipment at appropriate scale for the laboratory, with the necessary measurement instruments to analyze the behavior of heat energy transfer by means of thermocouples, the velocity of the air with a hot wire anemometer and the flow of water with a turbine flow meter, in pipes of different materials: copper, steel 1018 and stainless steel 316L, all in ideal conditions, and with this to found a comparative parameter with pipes of the same materials but under conditions of deterioration with the presence of forced oxidation and with the data mining and support vector machine can be minimized the corrosion problems in pipes.

INGENIERÍA Y TECNOLOGÍA CIENCIAS TECNOLÓGICAS Data Mining, Support Vector Machine, Pattern Recognition and Decision Support System, heat exchangers.

Implementation of a Nickel-Electroless Coating in Heat Exchanger Pipes Considering the Problem of the Environmental Conditions ofthe Cooling Water Without Recirculation to Increase the Effectiveness Under Uncertainty

VICTOR MANUEL ZEZATTI FLORES GUSTAVO URQUIZA BELTRAN MIGUEL ANGEL BASURTO PENSADO LAURA LILIA CASTRO GOMEZ JUAN CARLOS GARCIA CASTREJON (2022, [Artículo])

This research is based on the operation tube heat exchangers, their use and problematic on hydroelectric power plants. It is based on the design heat exchanger tubes for industrial use, which took the parameters of operation, design, working fluids (air and water) and conditions to assemble a monitoring equipment at appropriate scale for the laboratory, with the necessary measurement instruments to analyze the behavior of heat energy transfer by means of thermocouples, the velocity of the air with a hot wire anemometer and the flow of water with a turbine flow meter, in pipes of different materials: copper, steel 1018 and stainless steel 316L, all in ideal conditions, and with this to found a comparative parameter with pipes of the same materials but under conditions of deterioration with the presence of forced oxidation and with the data mining and support vector machine can be minimized the corrosion problems in pipes.

INGENIERÍA Y TECNOLOGÍA CIENCIAS TECNOLÓGICAS Data mining, Support Vector Machine, Pattern Recognition and Decision Support System, Heat exchangers

Modelado y acoplamiento de la conductividad eléctrica e hidráulica a partir de tomografía de rocas

Modeling and coupling of electrical and hydraulic conductivity from rock tomography

Miguel Ángel Martínez Rodríguez (2022, [Tesis de maestría])

En este trabajo se emplearon técnicas de modelado numérico para simular el flujo de corriente eléctrica y de fluido a través de medios porosos con el fin de determinar el factor de resistividad y la permeabilidad, así como la distribución de los campos de densidad de corriente eléctrica y velocidad de flujo. Para el modelado de flujo eléctrico se desarrolló un algoritmo basado en diferencias finitas, mientras que para el modelado hidráulico se empleó una librería reportada en la literatura, basada en el método de redes de Boltzmann. En ambos esquemas de modelado se establecieron condiciones en la frontera poro-grano para modelar los procesos físicos exclusivamente en el espacio poroso. Los valores estimados de factor de resistividad y de permeabilidad, así como la porosidad, se emplearon para estudiar las correlaciones entre estas propiedades a través de relaciones petrofísicas. Para esto, se propuso una expresión que relaciona la permeabilidad y la porosidad y, empleando una relación existente entre el factor de resistividad y la porosidad, se propuso también una relación directa entre la permeabilidad y el factor de resistividad. Las relaciones propuestas fueron aplicadas a los valores numéricos obtenidos para paquetes de esferas generados numéricamente y se encontró que se ajustan mejor a los datos en comparación con las relaciones más comúnmente utilizadas, especialmente para porosidades altas. Se mostró también que estas relaciones petrofísicas toman la forma de las relaciones más comunes conocidas cuando se trata con porosidades bajas. Valores obtenidos de imágenes digitales de un paquete de esferas sintético y una muestra de dolomita mostraron que las expresiones para porosidades bajas son suficientes para ajustar datos de medios porosos con porosidades menores a un valor entre 0.3 y 0.4. Finalmente, se analizaron el factor de resistividad, la permeabilidad, las relaciones petrofísicas, y las distribuciones espaciales y estadísticas de los campos vectoriales de flujo se analizaron para comparar los fenómenos de transporte eléctrico e hidráulico, encontrando que algunos factores, como la porosidad efectiva, son importantes en ambos fenómenos de flujo; mientras que otros, como la adherencia del fluido a las paredes del poro, son particularmente relevantes para el flujo hidráulico.

In this work, numerical modeling techniques were used to simulate the flow of electric current and fluid through porous media in order to determine the resistivity factor and permeability, as well as the distribution of electric current density and flow velocity fields. For electric flow modeling, an algorithm based on finite differences was developed, while for hydraulic modeling, a library reported in the literature, based on lattice Boltzmann method, was used. In both modeling schemes, pore-grain boundary conditions were established to model the physical processes exclusively in the pore space. The estimated values of resistivity factor and permeability, as well as porosity, were used to study the correlations between these properties through petrophysical relationships. An expression relating permeability and porosity was proposed and, using an existing relationship between the resistivity factor and the porosity, a direct relation between permeability and resistivity factor was also proposed. The proposed relations were applied to data obtained for numerically generated sphere packs and were found to fit the data better than the most commonly used relationships, especially for high porosities. It was also shown that these petrophysical relationships take the form of the most common relationships known when dealing with low porosities. Modeling data on digital images of a synthetic sphere pack and a dolomite sample showed that the expressions for low porosities are sufficient to fit data from porous media with porosities lower than 0.3 to 0.4. Finally, resistivity factors, permeabilities, petrophysical relationships, and spatial and statistical distributions of flow vector fields were analyzed to compare electrical and hydraulic transport phenomena, finding that some factors, such as the effective porosity, are important in both flow phenomena; whereas some other, such as the pore-wall adherence, are particularly relevant to hidraulic flux.

Física de rocas, modelado numérico, relaciones petrofísicas, fenómenos de transporte, factor de resistividad, permeabilidad, porosidad, tomografía de rocas, campos vectoriales, distribución estadística Rock physics, numerical modelling, petrophysical relations, transport phenomena, resistivity factor, permeability, porosity, rock tomography, vector fields, statistical distribution CIENCIAS FÍSICO MATEMÁTICAS Y CIENCIAS DE LA TIERRA CIENCIAS DE LA TIERRA Y DEL ESPACIO GEOFÍSICA GEOFÍSICA DE LA MASA SÓLIDA TERRESTRE GEOFÍSICA DE LA MASA SÓLIDA TERRESTRE

Suppression of breast tumor growth and metastasis by an engineered transcription factor

Adriana Beltran Lopez (2011, [Artículo])

Maspin is a tumor and metastasis suppressor playing an essential role as gatekeeper of tumor progression. It is highly expressed in epithelial cells but is silenced in the onset of metastatic disease by epigenetic mechanisms. Reprogramming of Maspin epigenetic silencing offers a therapeutic potential to lock metastatic progression. Herein we have investigated the ability of the Artificial Transcription Factor 126 (ATF-126) designed to upregulate the Maspin promoter to inhibit tumor progression in pre-established breast tumors in immunodeficient mice. ATF-126 was transduced in the aggressive, mesenchymal-like and triple negative breast cancer line, MDA-MB-231. Induction of ATF expression in vivo by Doxycycline resulted in 50% reduction in tumor growth and totally abolished tumor cell colonization. Genome-wide transcriptional profiles of ATF-induced cells revealed a gene signature that was found over-represented in estrogen receptor positive (ER+) "Normal-like" intrinsic subtype of breast cancer and in poorly aggressive, ER+ luminal A breast cancer cell lines. The comparison transcriptional profiles of ATF-126 and Maspin cDNA defined an overlapping 19-gene signature, comprising novel targets downstream the Maspin signaling cascade. Our data suggest that Maspin up-regulates downstream tumor and metastasis suppressor genes that are silenced in breast cancers, and are normally expressed in the neural system, including CARNS1, SLC8A2 and DACT3. In addition, ATF-126 and Maspin cDNA induction led to the re-activation of tumor suppressive miRNAs also expressed in neural cells, such as miR-1 and miR-34, and to the down-regulation of potential oncogenic miRNAs, such as miR-10b, miR-124, and miR-363. As expected from its over-representation in ER+ tumors, the ATF-126-gene signature predicted favorable prognosis for breast cancer patients. Our results describe for the first time an ATF able to reduce tumor growth and metastatic colonization by epigenetic reactivation of a dormant, normal-like, and more differentiated gene program. © 2011 Beltran et al.

artificial transcription factor 126, complementary DNA, doxycycline, estrogen receptor, maspin, microRNA, retrovirus vector, transcription factor, unclassified drug, estrogen receptor, serine proteinase inhibitor, SERPIN B5, SERPIN-B5, transcription BIOLOGÍA Y QUÍMICA CIENCIAS DE LA VIDA BIOLOGÍA ANIMAL (ZOOLOGÍA) BIOLOGÍA ANIMAL (ZOOLOGÍA)