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El futuro de la medicina está en tu boca: Las células madre de los dientes

ANGELICA ANAHI SERRALTA INTERIAN SOLEDAD MARIA TERESA HERNANDEZ SOTOMAYOR BEATRIZ ADRIANA RODAS JUNCO (2022, [Artículo])

En el cuerpo humano se han identificado varias fuentes de células madre; sin embargo, los dientes representan una nueva alternativa para la obtención de estas, debido a su fácil obténción, compatibilidad con biomateriales y escasos conflictos éticos; principalmente se han estudiado los tejidos de pulpa dental y ligamento periodontal, de los cuales se han logrado obtener diferentes tipos celulares que tienen el potencial de ser utilizadas para desarrollar estrategias para el tratamiento de enfermedades o la regeneración de órganos y tejidos.

CELULAS DENTALES LIGAMENTO PERIODONTAL LINAJE CELULAR PULPA DENTAL REGENERACION BIOLOGÍA Y QUÍMICA CIENCIAS DE LA VIDA BIOLOGÍA MOLECULAR BIOLOGÍA MOLECULAR DE PLANTAS BIOLOGÍA MOLECULAR DE PLANTAS

Síncrono / asíncrono. Convergencia y alternancia en la enseñanza futura del diseño

Francisco Gerardo Toledo Ramirez (2023, [Capítulo de libro])

La cuarentena sanitaria de los últimos dos años (COVID-19) obligó a “rediseñar”, “digitalizar” o “virtualizar” nuestros cursos y estilos de enseñanza en tiempo récord para “adaptarlas” al “formato virtual a distancia” (online). La profusión de comillas en las líneas anteriores tiene la intención de señalar el carácter incierto o erróneo que ciertos términos-fetiche adquirieron en el proceso. Es importante desmitificar esas figuras de la expresión que se elevaron casi al nivel de pseudo-epistemes (presuntamente novedosas) para la enseñanza del Diseño. Ese tema lo abordo con mayor amplitud en una nueva investigación, recientemente registrada en la UAM. En este texto esbozo (en forma algo lúdica) pero seria y breve a la vez, la conveniencia de tal desmitificación y avanzo en el delineamiento de un modelo de la alternancia y convergencia de recursos pedagógico-didácticos síncronos y asíncronos, mediante la tecnología-red digital, como un elemento estratégico para la educación futura en Diseño.

The health quarantine of the last 2 years (COVID-19) forced us to “redesign”, “digitize” or “virtualize” our courses and teaching styles in record time to “adapt” them to the “virtual format” “at a distance” (online). The profusion of quotation marks in the previous lines is intended to indicate the uncertain or erroneous character that certain fetish-terms acquired in the process. It is important to demystify those figures of expression that have risen almost to the level of pseudo-epistemes (presumably novel) for teaching design. I address this topic more fully in a new investigation, recently registered at the UAM. In this text I outline (in a somewhat playful way) but serious and brief at the same time, the convenience of such “demystification” and I advance in the outline of a model of alternation and convergence of synchronous and asynchronous pedagogical-didactic resources, through technology. -digital network, as a strategic element for future design education.

Síncrono, asíncrono, virtualidad, presencialidad, diseño, remoto. Synchronous, asynchronous, virtuality, face-to-face, design, remote. Design--Study and teaching, Higher. Distance education. Blended learning. Universidad Autónoma Metropolitana. Unidad Azcapotzalco. División de Ciencias y Artes para el Diseño. Artes gráficas. Educación a Distancia. Aprendizaje combinado. NK1170 HUMANIDADES Y CIENCIAS DE LA CONDUCTA CIENCIAS DE LAS ARTES Y LAS LETRAS

The banana MaWRKY18, MaWRKY45, MaWRKY60 and MaWRKY70 genes encode functional transcription factors and display differential expression in response to defense phytohormones

SERGIO GARCIA LAYNES VIRGINIA AURORA HERRERA VALENCIA Lilia Guadalupe Tamayo Torres VERONICA LIMONES BRIONES FELIPE ALONSO BARREDO POOL FRAY MARTIN BAAS ESPINOLA Angel Alpuche-Solis CARLOS ALBERTO PUCH HAU SANTY PERAZA ECHEVERRIA (2022, [Artículo])

WRKY transcription factors (TFs) play key roles in plant defense responses through phytohormone signaling pathways. However, their functions in tropical fruit crops, especially in banana, remain largely unknown. Several WRKY genes from the model plants rice (OsWRKY45) and Arabidopsis (AtWRKY18, AtWRKY60, AtWRKY70) have shown to be attractive TFs for engineering disease resistance. In this study, we isolated four banana cDNAs (MaWRKY18, MaWRKY45, MaWRKY60, and MaWRKY70) with homology to these rice and Arabidopsis WRKY genes. The MaWRKY cDNAs were isolated from the wild banana Musa acuminata ssp. malaccensis, which is resistant to several diseases of this crop and is a progenitor of most banana cultivars. The deduced amino acid sequences of the four MaWRKY cDNAs revealed the presence of the conserved WRKY domain of ~60 amino acids and a zinc-finger motif at the N-terminus. Based on the number of WRKY repeats and the structure of the zinc-finger motif, MaWRKY18 and MaWRKY60 belong to group II of WRKY TFs, while MaWRKY45 and MaWRKY70 are members of group III. Their corresponding proteins were located in the nuclei of onion epidermal cells and were shown to be functional TFs in yeast cells. Moreover, expression analyses revealed that the majority of these MaWRKY genes were upregulated by salicylic acid (SA) or methyl jasmonate (MeJA) phytohormones, although the expression levels were relatively higher with MeJA treatment. The fact that most of these banana WRKY genes were upregulated by SA or MeJA, which are involved in systemic acquired resistance (SAR) or induced systemic resistance (ISR), respectively, make them interesting candidates for bioengineering broad-spectrum resistance in this crop. © 2022 by the authors.

BANANA TRANSCRIPTION FACTOR WRKY DEFENSE PHYTOHORMONES SALICYLIC ACID METHYL JASMONATE SAR ISR BROAD-SPECTRUM RESISTANCE BIOLOGÍA Y QUÍMICA CIENCIAS DE LA VIDA GENÉTICA GENÉTICA MOLECULAR DE PLANTAS GENÉTICA MOLECULAR DE PLANTAS

Solanum tuberosum Microtuber Development under Darkness Unveiled through RNAseq Transcriptomic Analysis

ELIANA VALENCIA LOZANO LISSET HERRERA ISIDRON Osiel Salvador Recoder-Meléndez Aarón Barraza Celis JOSE LUIS CABRERA PONCE (2022, [Artículo])

"Potato microtuber (MT) development through in vitro techniques are ideal propagules for producing high quality potato plants. MT formation is influenced by several factors, i.e., photoperiod, sucrose, hormones, and osmotic stress. We have previously developed a protocol of MT induction in medium with sucrose (8% w/v), gelrite (6g/L), and 2iP as cytokinin under darkness. To understand the molecular mechanisms involved, we performed a transcriptome-wide analysis. Here we show that 1715 up- and 1624 down-regulated genes were involved in this biological process. Through the protein–protein interaction (PPI) network analyses performed in the STRING database (v11.5), we found 299 genes tightly associated in 14 clusters. Two major clusters of up-regulated proteins fundamental for life growth and development were found: 29 ribosomal proteins (RPs) interacting with 6 PEBP family members and 117 cell cycle (CC) proteins. The PPI network of up-regulated transcription factors (TFs) revealed that at least six TFs–MYB43, TSF, bZIP27, bZIP43, HAT4 and WOX9–may be involved during MTs development. The PPI network of down-regulated genes revealed a cluster of 83 proteins involved in light and photosynthesis, 110 in response to hormone, 74 in hormone mediate signaling pathway and 22 related to aging."

transcriptome-wide analysis, microtubers, potato, Solanum tuberosum, darkness, cell cycle, ribosomal proteins, PEBP family genes, cytokinin BIOLOGÍA Y QUÍMICA CIENCIAS DE LA VIDA GENÉTICA GENÉTICA MOLECULAR DE PLANTAS GENÉTICA MOLECULAR DE PLANTAS