Título
Octopus maya white body show sex-specific transcriptomic profiles during the reproductive phase, with high differentiation in signaling pathways
Autor
Oscar Juárez
Colaborador
Laura Liliana López Galindo (Colaborador)
Leonel Pérez Carrasco (Colaborador)
María Asunción Lago Lestón (Colaborador)
CARLOS ROSAS VAZQUEZ (Colaborador)
Anna Di Cosmo (Colaborador)
Clara E. Galindo-Sánchez (Colaborador)
Nivel de Acceso
Acceso Abierto
Identificador alterno
doi: https://doi.org/10.1371/journal.pone.0216982
Materias
androgen receptor, integrin, mitogen activated protein kinase, neuropeptide, transcriptome, tumor necrosis factor, argonaute protein, corticotropin releasing factor receptor, corticotropin releasing factor receptor 2, DEAD box protein, estradiol 17be - (SCOPUS) BIOLOGÍA Y QUÍMICA - (CTI) CIENCIAS DE LA VIDA - (CTI) BIOLOGÍA ANIMAL (ZOOLOGÍA) - (CTI) BIOLOGÍA ANIMAL (ZOOLOGÍA) - (CTI)
Resumen o descripción
White bodies (WB), multilobulated soft tissue that wraps the optic tracts and optic lobes, have been considered the hematopoietic organ of the cephalopods. Its glandular appearance and its lobular morphology suggest that different parts of the WB may perform different functions, but a detailed functional analysis of the octopus WB is lacking. The aim of this study is to describe the transcriptomic profile of WB to better understand its functions, with emphasis on the difference between sexes during reproductive events. Then, validation via qPCR was performed using different tissues to find out tissue-specific transcripts. High differentiation in signaling pathways was observed in the comparison of female and male transcriptomic profiles. For instance, the expression of genes involved in the androgen receptor-signaling pathway were detected only in males, whereas estrogen receptor showed higher expression in females. Highly expressed genes in males enriched oxidation-reduction and apoptotic processes, which are related to the immune response. On the other hand, expression of genes involved in replicative senescence and the response to cortisol were only detected in females. Moreover, the transcripts with higher expression in females enriched a wide variety of signaling pathways mediated by molecules like neuropeptides, integrins, MAPKs and receptors like TNF and Toll-like. In addition, these putative neuropeptide transcripts, showed higher expression in females’ WB and were not detected in other analyzed tissues. These results suggest that the differentiation in signaling pathways in white bodies of O. maya influences the physiological dimorphism between females and males during the reproductive phase. © 2019 Juárez et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Editor
Gao-Feng Qiu, Shanghai Ocean University, China
Fecha de publicación
2019
Tipo de publicación
Artículo
Versión de la publicación
Versión publicada
Recurso de información
Formato
application/pdf
Fuente
PLoS ONE, Vol.14, No.5, Pags. 1-29
Idioma
Inglés
Sugerencia de citación
Juárez OE, López-Galindo L, Pérez-Carrasco L, Lago-Lestón A, Rosas C, Di Cosmo A, et al. (2019) Octopus maya white body show sex-specific transcriptomic profiles during the reproductive phase, with high differentiation in signaling pathways. PLoS ONE 14(5): e0216982. https://doi.org/10.1371/journal.pone.0216982
Repositorio Orígen
Repositorio Institucional CICESE
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