Title

Preparation of quantum dots hydrogel nanocomposites with improved cytotoxicity

Author

ABRAHAM GONZALEZ RUIZ

MIGUEL ANGEL CAMACHO LOPEZ

MIRIAM VERONICA FLORES MERINO

Access level

Open Access

Summary or description

Nanocomposites are materials with unique properties and a wide range of applications. The combination of different nanostructures with traditional materials gives a variety of possibilities that should be analyzed. Especially, functional fluorescent semiconductor quantum dots (QDs) embedded in polymeric matrices have shown promising fluorescence and biocompatibility properties. These hybrid materials can be used in medical applications such as biodiagnostic and bioimaging. In this study, two hydrogels, one of polyethylene glycol diacrylate (PEGDA) and other of polyacrylamide (PAAm), were prepared with quantum dots of CdTe (4 nm of diameter) and characterized. The aim of this research was to analyze the optical properties of the nanocomposites and their cell viability. QDs nanocomposites were fabricated by a free radical polymerization process. The optical studies showed that the nanocomposites have well defined properties of fluorescence. To study the biocompatibility of the nanocomposites, metastatic B16f10 cell line were used and MTT assay was performed. The nanocomposites had a significant improved cell viability compared with QDs solutions.

Publisher

Journal of Nanoscience and Nanotechnology

Publish date

April 1, 2017

Publication type

Article

Source

1533-4899

Language

English

Relation

Vol.;17

Audience

Students

Researchers

Source repository

REPOSITORIO INSTITUCIONAL DE LA UAEM

Downloads

103

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