Título

Preparation of quantum dots hydrogel nanocomposites with improved cytotoxicity

Autor

ABRAHAM GONZALEZ RUIZ

MIGUEL ANGEL CAMACHO LOPEZ

MIRIAM VERONICA FLORES MERINO

Nivel de Acceso

Acceso Abierto

Licencia

http://creativecommons.org/licenses/by-nc-nd/4.0

Materias

quantum dots - ([1533-4899]) hydrogels - ([1533-4899]) cytotoxixity - ([1533-4899]) BIOLOGÍA Y QUÍMICA - (CTI)

Resumen o descripción

Nanocomposites are materials with unique properties and a wide range of applications. The combination of different nanostructures with traditional materials gives a variety of possibilities that should be analyzed. Especially, functional fluorescent semiconductor quantum dots (QDs) embedded in polymeric matrices have shown promising fluorescence and biocompatibility properties. These hybrid materials can be used in medical applications such as biodiagnostic and bioimaging. In this study, two hydrogels, one of polyethylene glycol diacrylate (PEGDA) and other of polyacrylamide (PAAm), were prepared with quantum dots of CdTe (4 nm of diameter) and characterized. The aim of this research was to analyze the optical properties of the nanocomposites and their cell viability. QDs nanocomposites were fabricated by a free radical polymerization process. The optical studies showed that the nanocomposites have well defined properties of fluorescence. To study the biocompatibility of the nanocomposites, metastatic B16f10 cell line were used and MTT assay was performed. The nanocomposites had a significant improved cell viability compared with QDs solutions.

Editor

Journal of Nanoscience and Nanotechnology

Fecha de publicación

1 de abril de 2017

Tipo de publicación

Artículo

Recurso de información

http://hdl.handle.net/20.500.11799/68854

Fuente

1533-4899

Idioma

Inglés

Relación

Vol.;17

Audiencia

Estudiantes

Investigadores

Repositorio Orígen

REPOSITORIO INSTITUCIONAL DE LA UAEM

Descargas

287