Título

HOW CAN WE DIAGNOSE TUBERCULOSIS MORE EFFECTIVELY?

Autor

MARIO ALBERTO FLORES VALDEZ

Nivel de Acceso

Acceso Abierto

Identificador alterno

doi: 10.3389/frym.2018.00036

Resumen o descripción

"Tuberculosis (TB) is a contagious disease that can be transmitted from a person who has the bacteria Mycobacterium tuberculosis within their lungs, and who expels the bacteria by coughing, allowing TB to infect other susceptible people. TB can affect people of all ages, from kids to the elderly, and in infected people, it often spreads to other organs, in addition to the lungs and can even spread throughout the body. Today, the most common way to diagnose TB is by staining the bacteria present in sputum (coughed up mucus) samples, using a chemical that will color those bacterial cells. However, in cases where the bacteria are located outside the lungs, this strategy is not effective. Furthermore, in some cases where coughed up mucus can be obtained, it could contain too few bacteria to easily detect them. Also, there are some people in which M. tuberculosis remains “dormant” or hiding, without causing trouble, but upon weakening of the immune (defense) system, the bacteria “wake up” and cause disease. Because of these complications, new strategies for diagnosis of TB rely on the use of samples other than coughed up mucus, in which M. tuberculosis can be detected using simple tests. In this article, I discuss how the immune response varies from person to person and even within the same person, how the immune response to M. tuberculosis changes with age or other circumstances, and how we could take advantage of these changes to improve diagnosis of TB."

Fecha de publicación

agosto de 2018

Tipo de publicación

Artículo

Versión de la publicación

Versión publicada

Formato

application/pdf

Fuente

Frontiers for Young Minds. 6:36.

Idioma

Inglés

Audiencia

Bibliotecarios

Estudiantes

Investigadores

Sugerencia de citación

Flores-Valdez M (2018) How Can We Diagnose Tuberculosis More Effectively?. Front. Young Minds. 6:36. doi: 10.3389/frym.2018.00036

Repositorio Orígen

Repositorio Institucional de CIATEJ

Descargas

229

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