Título
Preparation and characterization of coaxial electrospun fibers containing triclosan for comparative study of release properties with amoxicillin and epicatechin
Autor
DORA EVELIA RODRIGUEZ FELIX
MARIA MONICA CASTILLO ORTEGA
ALMA LETICIA NAJERA LUNA
ANA GABRIELA MONTAÑO FIGUEROA
ITZEL YANIRA LOPEZ PEÑA
TERESA DEL CASTILLO CASTRO
FRANCISCO RODRIGUEZ FELIX
JESUS MANUEL QUIROZ CASTILLO
PEDRO JESUS HERRERA FRANCO
Nivel de Acceso
Acceso Abierto
Referencia de datos
datasetDOI/DOI: 10.2174/1567201813666151204121752
Materias
Resumen o descripción
The optimal conditions for the fibers preparation of cellulose acetate (CA) and poly(vinyl pyrrolidone) (PVP) containing triclosan within the fiber were successfully found; the physicochemical characteristics of these fibrous membranes were corroborated by FTIR spectroscopy, thermal analysis, mechanical tests, SEM , and TEM analysis. The formation of composite fibers of CA and PVP containing triclosan at the core of the fiber was evidenced. A comparative study of the release properties of amoxicillin, epicatechin or triclosan embedded into fibers CA/PVP/CA was performed. As more interactions of the drug with CA or PVP occur, slower release of the drug into the release medium takes place. Regarding the drug delivery system design, it is important to consider the possible molecular interactions between the material components and predict how fast or slow the drug will be delivered into the corresponding medium.
Fecha de publicación
2016
Tipo de publicación
Artículo
Versión de la publicación
Versión publicada
Recurso de información
Formato
application/pdf
Fuente
Current drug delivery, 13(1), 49-56, 2016
Idioma
Inglés
Relación
&
Herrera-Franco, P. J. (2016). Preparation and Characterization of Coaxial Electrospun Fibers Containing Triclosan for Comparative Study of Release Properties with Amoxicillin and Epicatechin. Current drug delivery, 13(1), 49-56.
Sugerencia de citación
Rodríguez-Félix, D. E., Castillo-Ortega, M. M., Nájera-Luna, A. L., Montaño-Figueroa, A. G., López-Peña, I. Y., Del Castillo-Castro, T., ...
Repositorio Orígen
Repositorio Institucional CICY
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