Título

Aza-Michael Additions of Benzylamine to Acrylates Promoted by Microwaves and Conventional Heating Using DBU as Catalyst via Solvent-Free Protocol

Autor

Jaime Escalante García

Nivel de Acceso

Acceso Abierto

Licencia

http://creativecommons.org/licenses/by/4.0

Identificador alterno

issn/2227-9717

Materias

BIOLOGÍA Y QUÍMICA - (CTI) QUÍMICA - (CTI) solvent free, β-aminoesters, microwaves, aza-Michaeladdition, DBU

Resumen o descripción

In recent years, the use of solvent-free reactions represents a challenge for organic chemists, since it would help to optimize methodologies and contribute to the development of sustainable chemistry. In this regard, our research group has intensified efforts in the search for reactions that can be carried out in the absence of a solvent. In this paper, we present a protocol for the aza-Michael addition of benzylamine to α,β-unsaturated esters to prepare N-benzylated β-amino esters in the presence of catalytic amounts of DBU (0.2 eq) via solvent-free reaction. Depending on the α,β-unsaturated esters, we observed a reduction in reaction times, with good to excellent yields for aza-Michael addition.

Editor

MDPI

Fecha de publicación

2023

Tipo de publicación

Artículo

Recurso de información

http://riaa.uaem.mx/handle/20.500.12055/4402

2227-9717

Formato

pdf

Idioma

Inglés

Relación

Processes

1

12

https://www.mdpi.com/2227-9717/12/1/34

Cobertura

MEX

Audiencia

Investigadores

Repositorio Orígen

Repositorio Institucional de Acceso Abierto de la Universidad Autónoma del Estado de Morelos

Descargas

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