Título

HOTAIR Knockdown Decreased the Activity Wnt/ß-Catenin Signaling Pathway and Increased the mRNA Levels of Its Negative Regulators in Hela Cells

Autor

ERIC GENARO SALMERON BARCENAS

BERENICE ILLADES AGUIAR

OSCAR DEL MORAL HERNANDEZ

ARTURO ORTEGA SOTO

DANIEL HERNANDEZ SOTELO

Nivel de Acceso

Acceso Abierto

Licencia

http://creativecommons.org/licenses/by-nc-nd/4.0

Materias

ß-catenin HOTAIR Methylation TET1 and hydroxymethylation Cellular Physiology Biochemistry MEDICINA Y CIENCIAS DE LA SALUD - (CTI) CIENCIAS MÉDICAS - (CTI) OTRAS ESPECIALIDADES MÉDICAS - (CTI)

Resumen o descripción

We thank Juan Francisco Leyva-Illades for editing the manuscript. This study was supported by grant from CONACYT (242812), México.

Background/Aims: HOTAIR is a long non-coding RNA that promotes the development of human cancer. TET1 enzyme is involved in DNA demethylation by oxidation of 5-methylcytocine and it is considered a tumor suppressor in some types of cancer. HOTAIR and TET1 are involved in modulation of the Wnt/ß-catenin signaling pathway, but their role in cervical cáncer remains to be elucidated.

Editor

Cellular Physiology and Biochemistry

Fecha de publicación

5 de diciembre de 2019

Tipo de publicación

Artículo

Recurso de información

http://ri.uagro.mx/handle/uagro/1178

Formato

application/pdf

Idioma

Inglés

Audiencia

Público en general

Repositorio Orígen

Repositorio Institucional de Ciencia Abierta de la Universidad Autónoma de Guerrero

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