Título

DEVELOPMENT OF HA - nAg COMPOSITE COATING FROM GREEN PROCESS FOR HIP APPLICATIONS

Autor

VICTOR MANUEL OROZCO CARMONA

ANTONIO SERGUEI LEDEZMA PEREZ

Nivel de Acceso

Acceso Abierto

Resumen o descripción

In this study, biological hydroxyapatite was obtained from bovine bones by thermal process. Then 0 and 1 % nano-silver

synthesized by Opuntia ficus (nopal) containing biological hydroxyapatite coatings on a Ti6Al4V substrate were developed by

atmospheric plasma spray (APS), and their antibacterial efficiency was evaluated in the following bacterial strains: Escherichia

coli, Staphylococcus aureus and Pseudomonas aeruginosa according to the JIS Z2801:2000 standard “Antimicrobial product-

Test for antimicrobial activity and efficacy”. Ion release test shows that the coating delivered silver ions below 0.05 ppm; as

well as calcium, potassium, magnesium and sodium ions (it are cell growing promoters). Scanning electron microscopy (SEM)

showed that nano-silver particles (nAg) were distributed on the coating surface. Energy-dispersive X-ray spectroscopy (EDX)

shows that apatite deposition occurs day by day, maintaining a Ca/P rate between 2.12 and 1.45. Biocompatibility properties

were evaluated with Allium cepa, lymphocytes (fresh blood) and mouse osteoblast cells (MC3T3) by Allium cepa assay, single

cell gel electrophoresis assay and Tali image cytometry.

Fecha de publicación

2016

Tipo de publicación

Memoria de congreso

Versión de la publicación

Versión enviada

Formato

application/pdf

Idioma

Inglés

Repositorio Orígen

Fuente de Objetos Científicos Open Access

Descargas

455

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