Systematic Literature Review on Smart Specialization: Future Prospects and Opportunities

Beatriz Rosas Michael Demmler (2023)

"Smart specialisation (SS) has been the new cohesion policy in the European Union during the last two periods. The present study aims to analyse the most relevant existing state-of-the-art literature on smart specialisation through a systematic and bibliometric review. Using the Web of Science bibliographic database, we analysed the content of 207 articles under the TCCM methodology and constructed a network of citations in order to summarize theories, characteristics, context and methods presented in existing studies on the topic. Our results show the theoretical and methodological gaps of the past, such as Entrepreneurial Discovery Process and SS indicators. These remain to the present day. The context analysis showed that the scope of smart specialisation extended beyond the frontiers of the European Union, given how it has been adopted by other countries as well. These results suggest the importance of developing a more robust theoretical, conceptual and methodological framework. Consequently, the guides need to be more accurate and should be continuously updated. Our results are valuable for the EDP actors and have policymaking implications".

Artículo

Especialización inteligente Estrategias de innovación regional Revisión de literatura sistemática Métodos de especialización inteligente Smart specialization Smart specialization methods CIENCIAS SOCIALES CIENCIAS SOCIALES

Transcriptome mining provides insights into cell wall metabolism and fiber lignification in Agave tequilana Weber

Luis Fernando Maceda Lopez ELSA BEATRIZ GONGORA CASTILLO Enrique Ibarra-Laclette DALIA C. MORAN VELAZQUEZ AMARANTA GIRON RAMIREZ Matthieu Bourdon José Luis Villalpando Aguilar Gabriela Chavez-Calvillo Toomer John Tang Parastoo Azadi Jorge Manuel Santamaría Fernández Itzel López-Rosas Mercedes G Lopez June Simpson FULGENCIO ALATORRE COBOS (2022)

Resilience of growing in arid and semiarid regions and a high capacity of accumulating sugar-rich biomass with low lignin percentages have placed Agave species as an emerging bioen-ergy crop. Although transcriptome sequencing of fiber-producing agave species has been explored, molecular bases that control wall cell biogenesis and metabolism in agave species are still poorly understood. Here, through RNAseq data mining, we reconstructed the cellulose biosynthesis pathway and the phenylpropanoid route producing lignin monomers in A. tequilana, and evaluated their expression patterns in silico and experimentally. Most of the orthologs retrieved showed differential expression levels when they were analyzed in different tissues with contrasting cellulose and lignin accumulation. Phylogenetic and structural motif analyses of putative CESA and CAD proteins allowed to identify those potentially involved with secondary cell wall formation. RT-qPCR assays revealed enhanced expression levels of AtqCAD5 and AtqCESA7 in parenchyma cells associated with extraxylary fibers, suggesting a mechanism of formation of sclerenchyma fibers in Agave similar to that reported for xylem cells in model eudicots. Overall, our results provide a framework for un-derstanding molecular bases underlying cell wall biogenesis in Agave species studying mechanisms involving in leaf fiber development in monocots. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.

Artículo

AGAVE CELL WALLS LIGNOCELLULOSE CAD PROTEIN CESA PROTEIN SCLERENCHYMA BIOLOGÍA Y QUÍMICA CIENCIAS DE LA VIDA GENÉTICA GENÉTICA MOLECULAR DE PLANTAS GENÉTICA MOLECULAR DE PLANTAS