Tensiones entre modelos de decisión tecnocráticos y democráticos frente a riesgos colectivos : estudio sobre la confrontación política en México durante la pandemia de COVID-19

Cuauhtémoc Mondragón López (2022, [Tesis de maestría])

COVID-19 (enfermedad); México; Aspectos políticos; COVID-19 (enfermedad); Aspectos sociales; Administración de las crisis; Aspectos sanitarios; Políticas públicas; Riesgo CIENCIAS SOCIALES CIENCIA POLÍTICA OTRAS ESPECIALIDADES POLÍTICAS OTRAS ESPECIALIDADES POLÍTICAS

A Computational Method for the Binding Mode Prediction of COX-1 and COX-2 Inhibitors: Analyzing the Union of Coxibs, Oxicams, Propionic and Acetic Acids

ESTEFANY BELLO VARGAS JOSE MARIO ORDOÑEZ PALACIOS (2023, [Artículo])

Among the biological targets extensively investigated to improve inflammation and chronic inflammatory conditions, cyclooxygenase enzymes (COXs) occupy a prominent position. The inhibition of these enzymes, essential for mitigating inflammatory processes, is chiefly achieved through Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). In this work, we introduce a novel method—based on computational molecular docking—that could aid in the structure-based design of new compounds or the description of the anti-inflammatory activity of already-tested compounds. For this, we used eight crystal complexes (four COX-1 and COX-2 each), and each pair had a specific NSAID: Celecoxib, Meloxicam, Ibuprofen, and Indomethacin. This selection was based on the ligand selectivity towards COX-1 or COX-2 and their binding mode. An interaction profile of each NSAID was compiled to detect the residues that are key for their binding mode, highlighting the interaction made by the Me group. Furthermore, we rigorously validated our models based on structural accuracy (RMSD < 1) and (R2 > 70) using eight NSAIDs and thirteen compounds with IC50 values for each enzyme. Therefore, this model can be used for the binding mode prediction of small and structurally rigid compounds that work as COX inhibitors or the prediction of new compounds that are designed by means of a structure-based approach.

BIOLOGÍA Y QUÍMICA QUÍMICA anti-inflammatory, cyclooxygenase (COXs), molecular docking, NSAIDs, Celecoxib, Meloxicam, Ibuprofen,

Low nitrogen narrows down phenotypic diversity in durum wheat

Tesfaye Geleta Aga Bekele Abeyo (2023, [Artículo])

Clusters Durum Wheat Nitrogen Efficiency CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA HARD WHEAT GENETIC DIVERGENCE NORMALIZED DIFFERENCE VEGETATION INDEX NITROGEN PRINCIPAL COMPONENT ANALYSIS

Targeted nitrogen management to increase cereal production while reducing nitrogen consumption in India

Tek Sapkota Sieglinde Snapp (2022, [Objeto de congreso])

CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA CEREAL PRODUCTS PRODUCTION SYSTEMS CEREALS NITROGEN RICE WHEAT MAIZE

Biodiversity conservation in an anthropized landscape: Trees, not patch size drive, bird community composition in a low-input agroecosystem

ERIC MELLINK BIJTEL (2017, [Artículo])

One of the most typical agro-ecosystems in the Llanos de Ojuelos, a semi-arid region of central Mexico, is that of fruit-production orchards of nopales (prickly pear cacti). This perennial habitat with complex vertical structure provides refuge and food for at least 112 species of birds throughout the year. Nopal orchards vary in their internal structure, size and shrub/ tree composition, yet these factors have unknown effects on the animals that use them. To further understand the conservation potential of this agro-ecosystem, we evaluated the effects of patch-size and the presence of trees on bird community composition, as well as several habitat variables, through an information-theoretical modelling approach. Community composition was obtained through a year of census transects in 12 orchards. The presence of trees in the orchards was the major driver of bird communities followed by seasonality; bird communities are independent of patch size, except for small orchard patches that benefit black-chin sparrows, which are considered a sensitive species. At least 55 species of six trophic guilds (insectivores, granivores, carnivores, nectivores, omnivores, and frugivores) used the orchards. Orchards provide adequate habitat and food resources for several sensitive species of resident and migratory sparrows. The attributes that make orchards important for birds: trees, shrubs, herb seeds, and open patches can be managed to maintain native biodiversity in highly anthropized regions with an urgent need to find convergence between production and biological conservation. © 2017 Mellink et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

agroecosystem, carnivore, chin, conservation biology, driver, frugivore, granivore, habitat, human, insectivore, landscape, nonhuman, omnivore, orchard, resident, seasonal variation, shrub, sparrow, theoretical model, agriculture, animal, biodiversit CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA

Nanovacunas que valen oro

Carlos Eliud Angulo Valadez LUIS HERNANDEZ ADAME Ana Aguilera-Juarez (2022, [Artículo])

nanopartículas de oro BIOLOGÍA Y QUÍMICA CIENCIAS DE LA VIDA INMUNOLOGÍA VACUNAS VACUNAS

Danzas veracruzanas como grafías de la memoria. Recuerdos de indios, moros, negros y cristianos

GUADALUPE SANCHEZ ALVAREZ (2023, [Capítulo de libro])

Las danzas tradicionales, como las de los pueblos originarios del estado de Veracruz en México, son invaluables discursos históricos de la memoria. A través de ellas y su constante repetición, las comunidades y pueblos practicantes transmiten valores y consolidan sus identidades. Es por lo que se constituyen como complejos sistemas interculturales mantenedores de conocimiento, atributos por los cuales, necesitan ser replanteadas para un análisis en profundidad que vaya más allá de las formas prototípicas acostumbradas. Por lo anterior, en este trabajo se propone examinarlas desde el enfoque historiográfico, no sin antes repensarlas grafías no escriturarias, resultado de la sistematización historiográfica.

Traditional dances, such as those of peoples from the state of Veracruz in Mexico, are invaluable historical discourses of memory. Through them and their constant repetition, practicing communities and peoples transmit values and consolidate their identities. Therefore, they are constituted as complex intercultural systems maintaining knowledge, attributes by which, they need to be rethinker for an in-depth analysis that goes beyond the usual proto-typical forms. Therefore, in this work it is proposed to examine them from the historiographic approach, not without first rethink them nonwriting spellings, the result of historiographic systematization.

Danzas prehispánicas, enfoque historiográfico, memoria, identidad, Veracruz. Pre-Hispanic Dances, historiographical approach, memory, identity. Moros y Cristianos (Dance)--Mexico. Veracruz (Veracruz-Llave, Mexico) Group identity. Historiography. Danza indígena -- México. Veracruz (Veracruz) Identidad colectiva. Historiografía. GT4014.A2 CIENCIAS SOCIALES SOCIOLOGÍA SOCIOLOGÍA CULTURAL FOLKLORE

Redescription of Selenops minutus F.O. Pickard-Cambridge, 1900 (Aranei: Selenopidae)

DAVID CHAME VAZQUEZ MARIA LUISA JIMENEZ JIMENEZ CARLOS PALACIOS CARDIEL (2022, [Artículo])

"In this work we redescribe and rediagnose both sexes of the flattie spider Selenops minutus F.O. Pickard-Cambridge, 1900. In addition, we provide the first record of S. minutus from Mexico."

Araneae, new record, flattie spider, Chiapas, Mexico BIOLOGÍA Y QUÍMICA CIENCIAS DE LA VIDA BIOLOGÍA ANIMAL (ZOOLOGÍA) TAXONOMÍA ANIMAL TAXONOMÍA ANIMAL

Genetic analysis of Vibrio parahaemolyticus O3:K6 strains that have been isolated in Mexico since 1998

CARLOS ABRAHAM GUERRERO RUIZ (2017, [Artículo])

Vibrio parahaemolyticus is an important human pathogen that has been isolated worldwide from clinical cases, most of which have been associated with seafood consumption. Environmental and clinical toxigenic strains of V. parahaemolyticus that were isolated in Mexico from 1998 to 2012, including those from the only outbreak that has been reported in this country, were characterized genetically to assess the presence of the O3:K6 pandemic clone, and their genetic relationship to strains that are related to the pandemic clonal complex (CC3). Pathogenic tdh+ and tdh+/trh+ strains were analyzed by pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST). Also, the entire genome of a Mexican O3:K6 strain was sequenced. Most of the strains were tdh/ORF8-positive and corresponded to the O3:K6 serotype. By PFGE and MLST, there was very close genetic relationship between ORF8/O3:K6 strains, and very high genetic diversities from non-pandemic strains. The genetic relationship is very close among O3:K6 strains that were isolated in Mexico and sequences that were available for strains in the CC3, based on the PubMLST database. The whole-genome sequence of CICESE-170 strain had high similarity with that of the reference RIMD 2210633 strain, and harbored 7 pathogenicity islands, including the 4 that denote O3:K6 pandemic strains. These results indicate that pandemic strains that have been isolated in Mexico show very close genetic relationship among them and with those isolated worldwide. © 2017 Guerrero et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Article, bacterial strain, biofouling, controlled study, Crassostrea, food intake, gene sequence, genetic analysis, genetic variability, Japan, Mexican, Mexico, molecular phylogeny, nonhuman, pandemic, pathogenicity island, sea food, serotyping, toxi BIOLOGÍA Y QUÍMICA CIENCIAS DE LA VIDA GENÉTICA GENÉTICA

La enfermedad por coronavirus (COVID-19) y la iniciativa de excepción de los derechos de patente de las vacunas: oportunidades para México

Aradit Castellanos Vera Víctor Hugo Flores Delgado (2022, [Artículo])

"En este trabajo damos una visión general de la iniciativa que propone la excepción de los derechos de patente de las vacunas contra el virus de la COVID-19, del escenario de crisis global en la que surgió, así como de los principales argumentos de la controversia que la envuelve. En ese contexto analizamos y discutimos las medidas adoptadas por México para el aprovisionamiento de vacunas y las posibles oportunidades que esta iniciativa le brinda."

"In this paper we give an overview of the initiative that proposes the exception of patent rights for vaccines against the COVID-19, the global crisis scenario in which it arose, as well as the main arguments of the controversy that surrounds it. In this context, we analyze and discuss the measures adopted by Mexico for the supply of vaccines and the possible opportunities that this initiative offers."

excepción de patentes, vacunas, COVID-19, México patents waiver, vaccines, COVID-19, México MEDICINA Y CIENCIAS DE LA SALUD CIENCIAS MÉDICAS FARMACOLOGÍA NORMALIZACIÓN DE LOS MEDICAMENTOS NORMALIZACIÓN DE LOS MEDICAMENTOS